Research into physical, informational and biological systems. Mathematical modelling, cosmology, computational methods, oncology and neurorehabilitation.
Explore our research →Discover the instituteInterdisciplinary research grounded in mathematical models, data analysis, hypothesis testing and reproducible methodology.
The study of cosmological models, physical fields and their underlying assumptions.
02Modelling irreversibility, computational efficiency and decision-making processes.
03Oncology, neurorehabilitation, systems biology and the analysis of physiological data.
Our research programmes are presented through scholarly texts, methods, publications and available analytical results.
A theoretical framework for describing the information and energy costs of decisions.
Preprint / modellingHypotheses about cosmological dynamics and their comparison with standard models.
Pilot researchResearch indicators of stability in physiological time series. Clinical validation remains an open question.
The institute's research programmes combine mathematical and physical modelling with complex systems analysis, computer science and biomedicine. We emphasise methodological rigour, reproducibility and critical testing of results.
Collaboration opportunities →Scholarly and accessible articles with original visualisations on physics, biomedical modelling and cosmology.

Information-Energetic Thermodynamics seeks a common description of information, energy costs and irreversibility in the physical processing of information.

PSI is a research concept for investigating whether changes in system stability can be detected in physiological time series.

OSD explores whether the tumour environment can be described through biological states and transitions between them.

Alternative cosmological models are meaningful only when tested against established data and reference models.

Investigating information–energy efficiency requires metrics that can be tested on open data and appropriate benchmark scenarios.
Further applications of dynamical systems research: PSI and financial markets → · PSI and volcanic systems →. The methods differ, and each requires independent validation.
We model biological-state dynamics, investigate physiological stability and formulate testable hypotheses for oncology and neurorehabilitation.
OSD · PSI · NeuroCodec · Systems medicine
Explore medical research →
IRSFP research outputs include tumour systems biology (OSD), an experimental OSD protocol, Valid State Transition Framework methodology (VSTF), and the theoretical PSI–NeuroCodec neurorehabilitation framework. Bibliographic records and full texts are accessible through DOI links. The publication and validation status of each manuscript is stated.